The Benaroya Research Institute is offering an opportunity for an early career clinical scientist to join our Center for Interventional Immunology.  As a leader in immunology discovery and clinical research, the Benaroya Research Institute in Seattle, WA provides a unique environment for a physician investigator to focus on understanding the immune and metabolic causes and consequences of human autoimmunity and Type 1 diabetes.  We offer a superb training environment for early investigators. The BRI faculty include outstanding NIH funded laboratory and clinically based investigators providing a robust scientific milieu and focused mentorship to facilitate the development of clinician scientists.  Our group has leadership roles in NIH sponsored programs such as Diabetes TrialNet and the Immune Tolerance Network providing networking opportunities for early career investigators.  Based in Seattle, we are in a robust research environment with established collaborations in teaching and/or research with the University of Washington, Fred Hutch Cancer Center, Seattle Children’s Hospital and Research Institute, and industry partners. For pediatricians, the position may include joint clinical appointments with Seattle Children’s Hospital.

Combatting Immune Disease Through Data Analysis! Join our team to help fight immune diseases.    We need individuals to apply cutting edge statistical approaches to study the human immune system. We believe that understanding how the immune system functions both in health and in diseases like cancer and autoimmunity will lead to better patient care. We are looking for highly motivated and creative individuals who enjoy working in a multidisciplinary team-oriented environment to use statistical and computational approaches to discover new mechanisms, biomarkers, and therapies for immune-mediated diseases. The biostatistician will integrate with two teams: 1) our Center for Systems Immunology, a dynamic group of bioinformaticians, immunologists, and other data analysts, and 2) the Center for Interventional Immunology to help design and analyze data from clinical research studies.   Benaroya Research Institute at Virginia Mason (BRI) is an internationally recognized medical research institute committed to finding a cure for autoimmune and immune-mediated diseases, through a combination of basic and translational research programs. This means you can contribute to scientific advances that have a direct impact on people with these diseases, including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies, and asthma.

Combatting Immune Disease Through Data Analysis! Join our team to help fight immune diseases.    We need individuals to apply cutting edge statistical approaches to study the human immune system. We believe that understanding how the immune system functions both in health and in diseases like cancer and autoimmunity will lead to better patient care. We are looking for highly motivated and creative individuals who enjoy working in a multidisciplinary team-oriented environment to use statistical and computational approaches to discover new mechanisms, biomarkers, and therapies for immune-mediated diseases. The biostatistician will integrate with two teams: 1) our Center for Systems Immunology, a dynamic group of bioinformaticians, immunologists, and other data analysts, and 2) the Center for Interventional Immunology to help design and analyze data from clinical research studies.   Benaroya Research Institute at Virginia Mason (BRI) is an internationally recognized medical research institute committed to finding a cure for autoimmune and immune-mediated diseases, through a combination of basic and translational research programs. This means you can contribute to scientific advances that have a direct impact on people with these diseases, including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies, and asthma.

The Center for Systems Immunology at Benaroya Research Institute (BRI) in Seattle, WA seeks to recruit outstanding applicants for a new faculty position at the assistant or associate level. We seek candidates who use experimental and/or computational systems approaches that can be applied to study immune system functions in health and disease, with a particular emphasis on autoimmune diseases, mucosal immunology, allergy and cancer. This position offers a unique opportunity to bridge cutting-edge systems approaches with world class research in basic and translational immunology in a highly interactive and collaborative environment. Current research in the center includes programs aimed at identifying molecular signatures of pathogenic immune cells and determining how genetic variation tunes immune cell responses using the latest single cell and genetic screening approaches. The Center for Systems Immunology offers state of the art laboratory and sequencing resources, with a dedicated computational cluster, genomics core, and bioinformatics group with expertise in integrating and analyzing the latest sequencing and cytometry-based technologies. As part of the Seattle research community, BRI benefits from a rich and collaborative academic environment, with multiple major universities, research institutions, hospitals, and industry partners in close proximity. About BRI.  BRI is one of the few research institutes in the world devoted to finding causes and cures for immune system diseases and is an international leader in translating discoveries in autoimmune diseases to real life applications. Research at BRI encompasses many approaches, from studies of fundamental immunology processes, genetics and translational studies, to clinical trials. BRI is powered by excellent laboratory facilities, an extensive biorepository of samples from autoimmune patients and healthy subjects, and houses two international clinical research networks, the Immune Tolerance Network and Type 1 Diabetes TrialNet. Read more about BRI at www.benaroyaresearch.org.

The Benaroya Research Institute (BRI) seeks to recruit outstanding applicants for a new Assistant/Associate Member faculty position to join our Center for Interventional Immunology. As a leader in immunology discovery and clinical research, the Benaroya Research Institute in Seattle, WA provides a unique environment for an investigator to focus on understanding the causes and consequences of human autoimmunity including Type 1 diabetes.  BRI offers a superb training environment for early investigators. The BRI faculty include outstanding NIH funded laboratory and clinically based investigators providing a robust scientific milieu and focused mentorship to facilitate the development of researchers with a clinical research focus.  Our group has leadership roles in NIH sponsored programs such as Diabetes TrialNet and the Immune Tolerance Network providing networking opportunities for early career investigators.  Based in Seattle, we are in a robust research environment with established collaborations in teaching and/or research with the University of Washington, Fred Hutch Cancer Center, Seattle Children’s Hospital and Research Institute, and industry partners. The BRI Center for Interventional Immunology includes scientific and clinical investigators, clinicians, and a cadre of experienced clinical coordinators and support staff. Together, we conduct clinical trials designed to alter immune mediated disease such as type 1 diabetes, rheumatologic diseases and others.  We also conduct  clinical research investigations involving basic physiology studies and development and testing of biomarkers. In addition, the program maintains a robust immune mediated diseases registry and repository for translational studies. The repository contains thousands of patient samples well characterized by genetic, immune and clinical parameters.

The Animal Technician II-III provides for the basic health and husbandry needs of rodents (mice only) housed in the vivarium, processes equipment, and performs some colony management tasks. The job title and expected major responsibilities will be determined based on prior experience.   This is an essential position which means that punctuality as well as the ability to report to work, even during inclement weather, and on some holidays or other times when BRI suspends operations, is required. We are seeking a candidate to work 20 hours a week. The schedule for this position will be: Saturday and Sunday; 7:00am – 3:30pm. The remaining 4 hours to complete 20 hrs./week is negotiable.

The Harrison Lab studies the mechanisms controlling host-microbe interactions at barrier tissues, primarily the skin and the gut. We perform our research in a multidisciplinary and collaborative manner, combining in vivo cellular and molecular immunology, using genetic mouse models, microbiology, transcriptomic, and epigenetic analyses, to understand how commensal-specific immunity contributes to tissue homeostasis and repair.  This position is part-time (15 to 19 hours per week). 

The goal of the Harrison Lab is to understand how immune cells promote barrier tissue integrity and repair, and to understand how this goes awry during disease.  This work-study position is for 15 to 19 hours each week. 

The Khor laboratory is a high-mentoring environment currently seeking a highly motivated and creative individual for the position of Postdoctoral Research Associate. The scientist will be engaged in studying novel pathways regulating inflammation and autoimmunity, particularly in the context of Down syndrome. Work includes both human and animal models and is highly collaborative and cross-disciplinary. Immunology, in vivo mouse model and systems biology experience is highly desirable.  Our goal is to empower precision therapy of immune-medicated diseases in people with and without down syndrome.

The Khor laboratory is seeking a highly motivated and creative individual for the position of Research Technician I. The individual will be engaged in studying novel pathways regulating inflammation and autoimmunity, particularly in the context of Down syndrome. The individual will be responsible for providing technical laboratory support for biomedical research projects performing both routine and non-routine lab procedures. This is a transitory training position; the selected individual will receive strong mentoring to promote scientific growth and development.

The Clinical Research Assistant will work closely with the Center for Interventional Immunology study team to recruit and enroll participants, with and without autoimmune disease, conduct study visits and maintain study records in accordance with specified protocol and procedures for the Translational Research Program Immune Mediated Disease Registry and Repository.   This is not a lab-based position.

The Ray Lab is interested in better understanding how genetic variation tunes our immune system and how this can put individuals at risk for autoimmune diseases. In this position a student will learn biological laboratory techniques including DNA isolation, PCR, gel electrophoresis, molecular cloning as well as how to keep laboratory notes. This work-study position is for 10 to 15 hours each week. 

Combatting Immune Disease Through Genomics Analysis!  Come join our team and help fight immune diseases.    We need individuals to apply cutting edge big data approaches to study the human immune system. We believe that understanding how the immune system is broken in diseases like cancer and autoimmunity will lead to better patient care. We are looking for highly motivated and creative individuals who enjoy working in a multidisciplinary team-oriented environment to use Systems Biology approaches to discover new mechanisms, biomarkers and therapies for immune diseases.    Benaroya Research Institute at Virginia Mason (BRI) is an internationally recognized medical research institute committed to finding a cure for autoimmune and immune-mediated diseases, through a combination of basic and translational research programs. This means you can contribute to scientific advances that have a direct impact on people afflicted with these diseases, including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies, and asthma. BRI research leadership has identified Bioinformatics as a key enabling technology, so there is broad and strong support for the analysis, and visualization of research data.  

The Outreach Research Assistant is an essential member of the small team that promotes Benaroya Research Institute studies to patients, healthcare providers, and community groups, and that recruits participants for clinical trials and registries. The primary focus is type 1 diabetes (T1D) research, although the team will be asked to promote research participation for other immune system diseases. The person in this role has daily interaction with individuals and healthcare providers via phone calls, emails, and virtual and in-person meetings; and has strong writing and in-person communication skills. A background or interest in medical science is helpful to understand studies and describe them in lay language to potential participants and healthcare providers and in small group presentations.   The ideal person for this role is a self-starter with strong organizational skills who can prioritize tasks while working under deadlines. You must be able to work some evenings and weekends, and travel occasionally. Finally, you must be passionate about research that aims to improve the lives of people living with type 1 diabetes and other autoimmune diseases.   This is not a lab-based position.

The Buckner group studies the following autoimmune diseases: type 1 diabetes (T1D), rheumatoid arthritis (RA), multiple sclerosis (MS), systemic lupus erythematosus, and relapsing polychondritis. They have extensive experience in MHC class II tetramers, T cell cloning, T and B cell functional assays and phenotyping of human lymphocytes.