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The Harrison Lab at the Benaroya Research Institute (BRI) in Seattle, WA is seeking highly-motivated postdoctoral candidates in the areas of mucosal immunology, specifically T and B cell responses to commensal microbes. Benaroya Research Institute is an internationally recognized medical research institute focused on finding cures for autoimmune and immune-mediated diseases. We stress excellence in advanced laboratory experimentation and carefully designed translational research programs. This offers our scientists the opportunity to directly impact the lives of people suffering from diseases including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies and asthma. The Harrison Lab (www.harrison-lab.org) works to understand the mechanisms controlling host-microbe interactions at barrier sites such as the skin and gastrointestinal tract. We study how our resident commensal microbes influence the development, education and function of our immune system. To do so, we utilize a multi-disciplinary approach combining development and implementation of tools to track commensal-specific T and B cells in healthy and inflamed tissues, with single-cell and population level transcriptomics and epigenetic analyses of T and B cell differentiation to investigate how the host mounts and regulates immunity to the microbiome.
Requisition number
1597
Department
Harrison Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Kwok Lab at the Benaroya Research Institute in Seattle, Washington uses class II MHC multimer reagents and other state of art technologies, including single cell RNAseq experiments in examining antigen specific CD4+ T Cells in infectious diseases, peanut allergy, type 1 diabetes and rheumatoid arthritis.
Requisition number
1683
Department
Kwok Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Long Lab, at the Benaroya Research Institute, is a translational immunology lab focused on better understanding underlying mechanisms of the autoimmune disease, type 1 diabetes. This is done by performing mechanistic studies associated with clinical trials and in-depth studies using clinical samples.  In fact, we have been involved in the majority of studies cited in a recent Science T1D special section review (Science 373, 510-516, 2021).  This position provides the unique opportunity to focus on mechanistic studies associated with additional clinical trials in T1D targeting T cells or cytokine pathways.
Requisition number
1724
Department
Long Lab
Location : City
Seattle
Employment Type
Regular Full-Time
This highly collaborative 2+ year position, at the Benaroya Research Institute, provides a unique opportunity for multi-disciplinary research spanning Systems Immunologyand the Human Immunophenotyping (HIP) Core/Long Lab, under the guidance of Dr. Hamid Bolouri and Dr. Alice Long. The HIP Coreand Long Labare translational immunology labs that study autoimmunity by using cytometry-based assays on samples from clinical trials paired with selected samples to better understand mechanisms of disease.  The Bolouri Lab is focused on developing and applying computational systems immunology methods to better understand immune dysregulation in autoimmunity, cancer, and infection. We are seeking a bioinformatics scholar with strong interests in high-dimensional flow and mass cytometry, omics technologies, and systems immunology, as well as deep expertise in the development and application of bioinformatics methods and tools to emerging challenges in immunology research. Together, we hope to foster creative thinking that will move the field closer to treatments of immune mediated diseases.
Requisition number
1728
Department
HIP Core
Location : City
Seattle
Employment Type
Regular Full-Time
This highly collaborative postdoc position, at the Benaroya Research Institute, provides a unique opportunity for multi-disciplinary research spanning Systems Immunologyand the Human Immunophenotyping (HIP) Core/Long Lab, under the guidance of Dr. Hamid Bolouri and Dr. Alice Long at the Benaroya Research Institute.  The HIP Coreand Long Labare translational immunology labs that study autoimmunity by using cytometry-based assays on samples from clinical trials paired with selected samples to better understand mechanisms of disease.  The Bolouri Lab is focused on developing and applying computational systems immunology methods to better understand immune dysregulation in autoimmunity, cancer, and infection. We are seeking a bioinformatics scholar with strong interests in high-dimensional flow and mass cytometry, omics technologies, and systems immunology, as well as deep expertise in the development and application of bioinformatics methods and tools to emerging challenges in immunology research. Together, we hope to foster creative thinking that will move the field closer to treatments of immune mediated diseases.
Requisition number
1738
Department
HIP Core
Location : City
Seattle
Employment Type
Regular Full-Time
Combatting Immune Disease Through Genomics Analysis! Come join our team and help fight immune diseases.    We need individuals to apply cutting edge big data approaches to study the human immune system. We believe that understanding how the immune system is broken in diseases like cancer and autoimmunity will lead to better patient care. We are looking for highly motivated and creative individuals who enjoy working in a multidisciplinary team-oriented environment to use Systems Biology approaches to discover new mechanisms, biomarkers and therapies for immune diseases.    Benaroya Research Institute at Virginia Mason (BRI) is an internationally recognized medical research institute committed to finding a cure for autoimmune and immune-mediated diseases, through a combination of basic and translational research programs. This means you can contribute to scientific advances that have a direct impact on people afflicted with these diseases, including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies, and asthma. BRI research leadership has identified Bioinformatics as a key enabling technology, so there is broad and strong support for the analysis, and visualization of research data.  
Requisition number
1740
Department
Bioinformatics Group
Location : City
Seattle
Employment Type
Regular Full-Time
Combatting Immune Disease Through Systems Analysis    Come join our team and help fight immune diseases   Benaroya Research Institute needs individuals to apply cutting edge big data approaches to study of the human immune system. We believe that understanding how the immune system is broken in diseases like cancer and autoimmunity will lead to better patient care. We are looking for highly motivated and creative individuals who enjoy working in a multidisciplinary team-oriented environment to use Systems Biology approaches to help discover new mechanisms, biomarkers, and therapies for immune diseases. Successful candidates will receive a unique system of co-mentoring. They will reside in the Center for Systems Immunology at BRI and receive primary mentorship and training there. They will also collaborate closely with and be co-mentored by world class investigators expert in varied immune diseases and disease models throughout the Institute and elsewhere.
Requisition number
1741
Department
Bioinformatics Group
Location : City
Seattle
Employment Type
Regular Full-Time
The Clinical Research Program at the Benaroya Research Institute at Virginia Mason (BRI) is committed to giving patients access to clinical trials.  Working with clinicians at Virginia Mason Franciscan Health (VMFH), the Clinical Research Program at BRI differentiates itself by focusing on patient-centered research.  BRI is an independent, non-profit organization with a culture based on the values of collaboration, respect, innovation and inquiry.  Team members work together to support patients and clinicians with the goal of better outcomes for all.   Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram,  LinkedIn or Twitter to learn more.   The Clinical Research Program (CRP) Specialist provides administrative support and independently coordinates projects within the CRP at Benaroya Research Institute. The CRP supports the implementation of clinical research studies at Virginia Mason Medical Center and the Benaroya Research Institute.
Requisition number
1742
Department
Clinical Research
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute at Virginia Mason has a bold mission: Predict, prevent, reverse and cure immune system diseases, from autoimmune disease to cancer to COVID-19. We examine the immune system in both health and disease to understand how disorders start and how to rebalance the immune system back to health. Equipped with innovative tools and robust biorepositories, our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for all. As an independent non-profit organization within Virginia Mason Franciscan Health, we collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care   This position is open to candidates located anywhere within the U.S.A. The candidate will have the option to work remotely from home.
Requisition number
1745
Department
Systems Immunology
Location : City
Seattle
Employment Type
Regular Full-Time
This translational immunologist collaborative position, at the Benaroya Research Institute, provides a unique opportunity to explore the potentially protective role of exhausted CD8 T cells in type 1 diabetes (T1D) by integrating immunology and systems biology skill sets. The Long Lab is a translational immunology lab focused on better understanding underlying mechanisms of autoimmune disease, patient variability, and response to therapy. Currently, we are primarily focused on three, inter-related projects in the setting of T1D: 1) Causes and consequences of reduced response to IL-2, 2) Differentiation and stability of CD8 T cell exhaustion associated with better outcome, and 3) identification of biomarkers of T1D severity. Each of these projects use human samples, are collaborative in context working with the diabetes team and systems immunology, and use the resources of the BRI Human Immunophenotyping (HIP) Core, supervised by Dr. Alice Long.
Requisition number
1747
Department
Long Lab
Location : City
Seattle
Employment Type
Regular Full-Time
This translational immunologist collaborative position provides a unique opportunity to explore the potentially protective role of exhausted CD8 T cells in type 1 diabetes (T1D) by integrating immunology and systems biology skill sets.   The Long Lab, at the Benaroya Research Institute, is a translational immunology lab focused on better understanding underlying mechanisms of autoimmune disease, patient variability, and response to therapy.  Currently, we are primarily focused on three, inter-related projects in the setting of T1D: 1) Causes and consequences of reduced response to IL-2, 2) Differentiation and stability of CD8 T cell exhaustion associated with better outcome, and 3) identification of biomarkers of T1D severity.    Each of these projects use human samples, are collaborative in context working with the diabetes team and systems immunology, and use the resources of the BRI Human Immunophenotyping (HIP) Core, supervised by Dr. Alice Long. 
Requisition number
1748
Department
Long Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Kwok Lab, at the Benaroya Research Institute (BRI) in Seattle, Washington is seeking a Postdoctoral Research Associate to join a lab that uses class II tetramer reagents and other state of art technologies, including single cell RNAseq experiments in examining antigen specific CD4+ T cells infectious diseases, peanut allergy, type 1 diabetes and rheumatoid arthritis.
Requisition number
1753
Department
Kwok Lab
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute at Virginia Mason (BRI) has a bold mission: Predict, prevent, reverse and cure immune system diseases, from autoimmune disease to cancer to COVID-19. We examine the immune system in both health and disease to understand how disorders start and how to rebalance the immune system back to health. Equipped with innovative tools and robust biorepositories, our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for all. As an independent non-profit organization within Virginia Mason Franciscan Health, we collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care.   At BRI, each role is valued and an important contributor to the vision and mission. BRI is committed to a safe, caring and diverse workplace; as well as to taking action to further our commitments to foster inclusion, equity and belonging so employees feel comfortable bringing their full selves to work. Consider making a difference, join our team. Because together, we are Powering Possibility.   Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram,  LinkedIn or Twitter to learn more.     The Research Assistant will work closely with the Translational Research Program study team to recruit and enroll participants, with and without autoimmune disease, conduct study visits and maintain study records in accordance with specified protocol and procedures for the Translational Research Program Immune Mediated Disease Registry and Repository. This is not a lab-based position.
Requisition number
1758
Department
Translational Research
Location : City
Seattle
Employment Type
Regular Full-Time
The Clinical Research Program at the Benaroya Research Institute at Virginia Mason (BRI) is committed to giving patients access to clinical trials.  Working with clinicians at Virginia Mason Franciscan Health (VMFH), the Clinical Research Program at BRI differentiates itself by focusing on patient-centered research.  BRI is an independent, non-profit organization with a culture based on the values of collaboration, respect, innovation and inquiry.  Team members work together to support patients and clinicians with the goal of better outcomes for all.   Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram,  LinkedIn or Twitter to learn more.   The Administrative Assistant II provides administrative support and independently coordinates projects within the CRP at Benaroya Research Institute. The CRP supports the implementation of clinical research studies at Virginia Mason Medical Center and the Benaroya Research Institute.
Requisition number
1763
Department
Clinical Research
Location : City
Seattle
Employment Type
Regular Full-Time
The Clinical Research Program at the Benaroya Research Institute at Virginia Mason (BRI) is committed to giving patients access to clinical trials.  Working with clinicians at Virginia Mason Franciscan Health (VMFH), the Clinical Research Program at BRI differentiates itself by focusing on patient-centered research.  BRI is an independent, non-profit organization with a culture based on the values of collaboration, respect, innovation and inquiry.  Team members work together to support patients and clinicians with the goal of better outcomes for all.   Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram,  LinkedIn or Twitter to learn more.   A Clinical Research Coordinator (CRC) I-II performs an increasing complexity of tasks to facilitate clinical research which may include working with affiliate or collaborating research sites as well as conducting BRI based research studies. This position is based in the Cancer Clinical Research Unit, with patient visits occurring in the downtown Seattle Virginia Mason outpatient oncology clinic. The CRC I-II will manage a variety of oncology trials in Phases I – III. This position functions as part of a highly dynamic team of Coordinators and Research Assistants (RA), and requires the candidate to be on-site a majority of the time.  
Requisition number
1765
Department
Clinical Research
Location : City
Seattle
Employment Type
Regular Full-Time
The Buckner Lab at the Benaroya Research Institute in Seattle, Washington is renowned for expertise in translational immunology and human autoimmune disease. Research in the Buckner Lab focuses on identifying the underlying mechanisms by which the adaptive immune response to self-antigen becomes pathogenic in the setting of human autoimmune study. They use cutting edge techniques and primary human immune cells to study the following autoimmune diseases: type 1 diabetes (T1D), rheumatoid arthritis (RA), muliple sclerosis (MS), systemic lupus erythematosus and irAE in Cancer immunotherapy.  They have extensive experience in MHC class II tetramers, T cell cloning, T and B cell functional assays, gene editing and phenotyping of human lymphocytes.   Potential projects in the Buckner Lab include: - Development of regulatory T cell - based therapies - Identification and characterization of antigen-specific T cells in rheumatoid arthritis - Genotype-phenotype studies of genetic variants associated with autoimmune disease - T cell response to cytokines in autoimmune disease. - irAE in the setting of cancer immunotherapies
Requisition number
1766
Department
Buckner Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Center for Systems Immunology at the Benaroya Research Institute (BRI) seeks to recruit an outstanding candidate for a Bioinformatics position in Dynamic Systems Biology. The goal of our group is to study and characterize the dynamical behavior of the immune system in health and disease and develop an operational understanding of how nonlinearities in interactions among the system components govern response to external perturbations such as vaccines and drugs. While our primary focus is the immune system, we explore longitudinal behavior with multiscale datasets including, but not limited to, cytometry, single- and bulk- RNA-seq, proteomics and perturbation-omics data. The phenomena that we study include all kinds of time-varying behavior such as breadth of immunotype heterogeneity across populations, resilience of immunotype variability over time, and acute responses to vaccines and drugs. The candidate will work closely with other bioinformaticians and immunologists at BRI, resulting in a rich environment for quantitative, computational, and laboratory collaborations in immune disease research. This position is open to candidates located anywhere within the U.S.A. The candidate will have the option to work remotely from home. 
Requisition number
1772
Department
Systems Immunology
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute at Virginia Mason (BRI) is an independent non-profit organization within Virginia Mason Franciscan Health.  We collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care.  This position is designed to provide monitoring services (approximately 65-75% of the time) for clinical research trials performed primarily at Virginia Mason Franciscan Health with a secondary responsibility to assist with staff training and education, document control, CAPA creation assistance and follow-up, and other study staff support as needed. Monitoring work typically focuses on moderate to high-risk studies, with special emphasis on Sponsor-Physician research and oncology studies. As an internal monitor, this position will work with the research staff to assure fundamental clinical research knowledge, mistake-proofing, and long-term success.
Requisition number
1774
Department
Research Integrity & Safety Department
Location : City
Seattle
Employment Type
Regular Full-Time
The Marketing and Communications Specialist is an essential position in the BRI Marketing and Communications department (MarCom) at the Benaroya Research Institute, a team of four members. The person in this role will produce and maintain inventory of high-quality communications materials, help to organize events, lead online and social media communications, and act as a media, community and internal liaison. This person will be responsible for a variety of day-to-day programmatic and administrative tasks for the department and will report to the Director of Marketing and Communications. The job requires a person who enjoys contributing to a team, who has excellent writing skills and is comfortable multi-tasking in a deadline-driven environment. This role requires an individual who is organized, a dependable self-starter and able to manage a number of tasks and projects. It is critical that this team member embrace both exciting and mundane tasks with equal gusto and attention. We offer a hybrid work schedule.
Requisition number
1776
Department
Marketing & Communications
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute at Virginia Mason (BRI) has a bold mission: Predict, prevent, reverse and cure immune system diseases, from autoimmune disease to cancer to COVID-19. We examine the immune system in both health and disease to understand how disorders start and how to rebalance the immune system back to health. Equipped with innovative tools and robust biorepositories, our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for all. As an independent non-profit organization within Virginia Mason Franciscan Health, we collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care.   At BRI, each role is valued and an important contributor to the vision and mission. BRI is committed to a safe, caring and diverse workplace; as well as to taking action to further our commitments to foster inclusion, equity and belonging so employees feel comfortable bringing their full selves to work. Consider making a difference, join our team. Because together, we are Powering Possibility.   Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram,  LinkedIn or Twitter to learn more.   The Ray Labat Benaroya Research Institute (BRI) in Seattle, WA is seeking a highly-motivated Research Technician I to join their hard-working, cutting-edge research team. The Ray lab studies how human genetic variation contributes to autoimmune disease susceptibility through altering immune cell function. The lab is currently focusing on multiple sclerosis, a debilitating neurological disease that affects 1M people in the US. To better understand genetic risk for this and other autoimmune diseases, the lab identifies regions that correlate with disease progression and perturbs those regions in primary human and mouse cells to determine their effects on immune cell function and disease. Assays include CRISPR-mediated silencing of active regions of the genome, DNA base editing, massively parallel reporter assays, and other methodologies and analyses to find regions of the genome that promote risk for disease. The Research Technician I will be responsible for assisting with the Ray Lab mouse colony, helping with autoimmune mouse model experiments, providing technical laboratory support, and performing both routine and non-routine lab procedures.
Requisition number
1777
Department
Ray Lab
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute at Virginia Mason (BRI) has a bold mission: Predict, prevent, reverse and cure immune system diseases, from autoimmune disease to cancer to COVID-19. We examine the immune system in both health and disease to understand how disorders start and how to rebalance the immune system back to health. Equipped with innovative tools and robust biorepositories, our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for all. As an independent non-profit organization within Virginia Mason Franciscan Health, we collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care.   At BRI, each role is valued and an important contributor to the vision and mission. BRI is committed to a safe, caring and diverse workplace; as well as to taking action to further our commitments to foster inclusion, equity and belonging so employees feel comfortable bringing their full selves to work. Consider making a difference, join our team. Because together, we are Powering Possibility.   Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram,  LinkedIn or Twitter to learn more.     While under direct supervision, the Helpdesk Technician I’s role is to ensure proper computer operation so that end users can accomplish business tasks. This includes receiving, prioritizing, documenting, and actively resolving end-user help requests. Problem resolution may involve the use of diagnostic and help request tracking tools and require that the individual give in-person, hands-on help at the desktop level.
Requisition number
1778
Department
Information Technology
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute at Virginia Mason (BRI) has a bold mission: Predict, prevent, reverse and cure immune system diseases, from autoimmune disease to cancer to COVID-19. We examine the immune system in both health and disease to understand how disorders start and how to rebalance the immune system back to health. Equipped with innovative tools and robust biorepositories, our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for all. As an independent non-profit organization within Virginia Mason Franciscan Health, we collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care.   At BRI, each role is valued and an important contributor to the vision and mission. BRI is committed to a safe, caring and diverse workplace; as well as to taking action to further our commitments to foster inclusion, equity and belonging so employees feel comfortable bringing their full selves to work. Consider making a difference, join our team. Because together, we are Powering Possibility.   Visit BenaroyaResearch.org or follow BRI’s Autoimmune Life Blog, Facebook, Instagram,  LinkedIn or Twitter to learn more.     The Clinical Research Accounting Specialist has primary responsibility for all aspects of invoicing and investigation of Clinical Research Program receivables.   This position is open to remote applicants.
Requisition number
1779
Department
Accounting
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute at Virginia Mason (BRI) is an independent non-profit organization within Virginia Mason Franciscan Health.  We collaborate with clinicians to accelerate the path from innovative lab discoveries to life-changing patient care. 
Requisition number
2022-1780
Department
Clinical Research
Location : City
Seattle
Employment Type
Regular Full-Time