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The Harrison Lab at the Benaroya Research Institute (BRI) in Seattle, WA is seeking highly-motivated postdoctoral candidates in the areas of mucosal immunology, specifically T and B cell responses to commensal microbes. Benaroya Research Institute is an internationally recognized medical research institute focused on finding cures for autoimmune and immune-mediated diseases. We stress excellence in advanced laboratory experimentation and carefully designed translational research programs. This offers our scientists the opportunity to directly impact the lives of people suffering from diseases including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies and asthma. The Harrison Lab (www.harrison-lab.org) works to understand the mechanisms controlling host-microbe interactions at barrier sites such as the skin and gastrointestinal tract. We study how our resident commensal microbes influence the development, education and function of our immune system. To do so, we utilize a multi-disciplinary approach combining development and implementation of tools to track commensal-specific T and B cells in healthy and inflamed tissues, with single-cell and population level transcriptomics and epigenetic analyses of T and B cell differentiation to investigate how the host mounts and regulates immunity to the microbiome.
Requisition number
1597
Department
Harrison Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Buckner Lab at the Benaroya Research Institute (BRI) in Seattle, WA. Studies the following autoimmune diseases: type 1 diabetes (T1D), rheumatoid arthritis (RA), multiple sclerosis (MS), systemic lupus erythematosus, and relapsing polychondritis. They have extensive experience in MHC class II tetramers, T cell cloning, T and B cell functional assays and phenotyping of human lymphocytes.
Requisition number
1672
Department
Buckner Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Khor laboratory at the Benaroya Research Institute (BRI) in Seattle, WA is seeking highly motivated and creative individuals for the position of Postdoctoral Research Associate. The scientist will be engaged in studying novel pathways regulating inflammation, autoimmunity and immune aging particularly in the context of Down syndrome. Work includes both human and animal models and involves multidisciplinary collaboration. Immunology, in vivo mouse model and systems biology experience is highly desirable.
Requisition number
1680
Department
Khor Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Kwok Labat the Benaroya Research Institute (BRI) in Seattle, WA. Uses class II tetramer reagents and other state of art technologies, including single cell RNAseq experiments in examining antigen specific CD4+ T cells infectious diseases, peanut allergy, type 1 diabetes and rheumatoid arthritis.
Requisition number
1682
Department
Kwok Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Kwok Lab uses class II MHC multimer reagents and other state of art technologies, including single cell RNAseq experiments in examining antigen specific CD4+ T Cells in infectious diseases, peanut allergy, type 1 diabetes and rheumatoid arthritis.
Requisition number
1683
Department
Kwok Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Cerosaletti lab at the Benaroya Research Institute (BRI) in Seattle, WA. We are engaged in translational research to identify key mechanisms in the development of autoimmunity and allergy.  Current projects in the lab are investigating autoreactive T cells in type 1 diabetes.
Requisition number
1690
Department
Cerosaletti Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Buckner group studies the following autoimmune diseases: type 1 diabetes (T1D), rheumatoid arthritis (RA), multiple sclerosis (MS), systemic lupus erythematosus, and relapsing polychondritis. They have extensive experience in MHC class II tetramers, T cell cloning, T and B cell functional assays and phenotyping of human lymphocytes.
Requisition number
1691
Department
Buckner Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Clinical Core Laboratory (CCL) at BRI provides sample processing, archiving and distribution services for clinical research projects conducted at BRI. While this is not a research position, the CCL’s sample management services are an integral part of the clinical research which takes place at BRI.
Requisition number
1707
Department
Clinical Core Lab
Location : City
Seattle
Employment Type
Regular Full-Time
Benaroya Research Institute (BRI) in Seattle, WA is seeking a bioinformatics and machine learning expert who has demonstrated experience working with large multi-omics, next-generation sequencing (bulk/single-cell) and single-cell cytometery datasets. Candidate should have working knowledge and skills in statistical analysis, regression analysis, graph theory, bayesian learning and other exploratory/inferential analytical tools. Individuals with background training in Dynamical Systems Analysis and/or Deep Learning are strongly encouraged to apply. The individual will join as a Postdoctoral Research Associate in the Systems Immunology Group which is broadly engaged in basic and applied studies using complex systems theory, high throughput techniques as well as mathematical and computational tools to understand the functioning of the immune system in health and disease. The group works closely with informaticians and immunologists in many groups at BRI, resulting in a rich environment for quantitative, computational, and laboratory collaborations in immune disease research. The candidate will implement bioinformatics analysis algorithms and develop analytical pipelines for extracting biomarkers from large time series datasets that will provide insights into mechanisms underlying successful response to treatment in clinical trials. This position is remote, and is open to candidates anywhere within the U.S.A. 
Requisition number
1714
Department
Systems Immunology
Location : City
Seattle
Employment Type
Regular Full-Time
This position is responsible for assisting the Grants & Contracts Director and team with operations. The Grants and Contracts Administration team manages cradle-to-grave support for sponsored research at BRI. This position is intended to be a support role and training position for individuals looking to learn the field and grow into greater responsibilities.  The Grants & Contracts department is working a hybrid schedule and provides some workplace flexibility though local applicants are preferred to meet the hybrid (some on-site days) expectations.   This is an entry-level position in the grants & contracts field.
Requisition number
1721
Department
Grants and Contracts
Location : City
Seattle
Employment Type
Regular Full-Time
The Long Lab is a translational immunology lab focused on better understanding underlying mechanisms of the autoimmune disease, type 1 diabetes. This is done by performing mechanistic studies associated with clinical trials and in-depth studies using clinical samples.  In fact, we have been involved in the majority of studies cited in a recent Science T1D special section review (Science 373, 510-516, 2021).  This position provides the unique opportunity to focus on mechanistic studies associated with additional clinical trials in T1D targeting T cells or cytokine pathways.
Requisition number
1724
Department
Long Lab
Location : City
Seattle
Employment Type
Regular Full-Time
This highly collaborative 2+ year position provides a unique opportunity for multi-disciplinary research spanning Systems Immunologyand the Human Immunophenotyping (HIP) Core/Long Lab, under the guidance of Dr. Hamid Bolouri and Dr. Alice Long. The HIP Coreand Long Labare translational immunology labs that study autoimmunity by using cytometry-based assays on samples from clinical trials paired with selected samples to better understand mechanisms of disease.  The Bolouri Lab is focused on developing and applying computational systems immunology methods to better understand immune dysregulation in autoimmunity, cancer, and infection. We are seeking a bioinformatics scholar with strong interests in high-dimensional flow and mass cytometry, omics technologies, and systems immunology, as well as deep expertise in the development and application of bioinformatics methods and tools to emerging challenges in immunology research. Together, we hope to foster creative thinking that will move the field closer to treatments of immune mediated diseases.
Requisition number
1728
Department
Human Immunophenotyping Core Laboratory (HIP-c)
Location : City
Seattle
Employment Type
Regular Full-Time
The Clinical Research Center (CRC) is an outpatient, hospital-based clinic which provides nursing services for pediatric and adult participants enrolled in research studies, with an emphasis on autoimmune diseases (particularly Type One Diabetes), and immune therapies. The Per Diem Research Nurse supports and supplements regular staff during high census days and in other special circumstances. The Research Nurse will support the CRC by providing various nursing services, including starting IVs, infusing investigational agents, performing blood draws, checking vital signs, monitoring for adverse events, and any other required nursing support to the research staff.  The Per Diem Research Nurse will cover primarily day shift hours, though evening and night shifts may periodically be offered. Due to the nature of scheduling on the CRC, the available shifts offered to the Per Diem pool often vary substantially from one month to the next. Flexibility and availability are key qualities in the Per Diem RN team.
Requisition number
1729
Department
Clinical Research Center
Location : City
Seattle
Employment Type
Temporary Part-Time
The Center for Translational Immunology studies the following autoimmune diseases: type 1 diabetes (T1D), rheumatoid arthritis (RA), multiple sclerosis (MS), systemic lupus erythematosus, and relapsing polychondritis. They have extensive experience in MHC class II tetramers, T cell cloning, T and B cell functional assays and phenotyping of human lymphocytes.
Requisition number
1731
Department
Center for Translational Immunology
Location : City
Seattle
Employment Type
Regular Full-Time
The Wambre Lab at the Benaroya Research Institute (BRI) in Seattle, WA is seeking  a Postdoctoral Research Associate who will be involved in research involving application of cutting edge cellular and molecular profiling techniques to current immunological problems in human health. Studies will focus on human antigen-specific CD4+ T cell responses including biomarker discovery in health and disease. Responsibilities include conceptualizing and executing experiments, data analysis, laboratory record keeping, oral and written presentation of experimental results. The position may involve oversight/ supervision of technicians or graduate students.
Requisition number
1733
Department
Wambre Lab
Location : City
Seattle
Employment Type
Regular Full-Time
The Wambre Lab at the Benaroya Research Institute (BRI) in Seattle, WA is seeking an independent, motivated and creative researcher for a Staff Scientist position in the field of immunotherapy. The successful candidate will develop and conduct independent discovery research projects to investigate ex vivo antigen-specific immune response using innovative immunological tools in clinically relevant samples. The Staff Scientist conducts independent biomedical research relevant to current projects at BRI.
Requisition number
1734
Department
Wambre Lab
Location : City
Seattle
Employment Type
Regular Full-Time
This highly collaborative postdoc position provides a unique opportunity for multi-disciplinary research  spanning Systems Immunologyand the Human Immunophenotyping (HIP) Core/Long Lab, under the guidance of Dr. Hamid Bolouri and Dr. Alice Long. The HIP Coreand Long Labare translational immunology labs that study autoimmunity by using cytometry-based assays on samples from clinical trials paired with selected samples to better understand mechanisms of disease.  The Bolouri Lab is focused on developing and applying computational systems immunology methods to better understand immune dysregulation in autoimmunity, cancer, and infection. We are seeking a bioinformatics scholar with strong interests in high-dimensional flow and mass cytometry, omics technologies, and systems immunology, as well as deep expertise in the development and application of bioinformatics methods and tools to emerging challenges in immunology research. Together, we hope to foster creative thinking that will move the field closer to treatments of immune mediated diseases.
Requisition number
1738
Department
Human Immunophenotyping Core Laboratory (HIP-c)
Location : City
Seattle
Employment Type
Regular Full-Time
The Animal Technician I-III provides for the basic health and husbandry needs of rodents (mice only) housed in the vivarium, processes equipment, and performs some colony management tasks. The job title and expected major responsibilities will be determined based on prior experience   This is an essential position which means that punctuality as well as the ability to report to work, even during inclement weather, and on some holidays or other times when BRI suspends operations, is required. Must be able to work a weekly schedule Saturday – Wednesday; 7:00am – 3:30pm. 
Requisition number
1739
Department
Animal Resources
Location : City
Seattle
Employment Type
Regular Full-Time
Combatting Immune Disease Through Genomics Analysis   Come join our team  and help fight immune diseases   We need individuals to apply cutting edge big data approaches to study the human immune system. We believe that understanding how the immune system is broken in diseases like cancer and autoimmunity will lead to better patient care. We are looking for highly motivated and creative individuals who enjoy working in a multidisciplinary team-oriented environment to use Systems Biology approaches to discover new mechanisms, biomarkers and therapies for immune diseases.    Benaroya Research Institute at Virginia Mason (BRI) is an internationally recognized medical research institute committed to finding a cure for autoimmune and immune-mediated diseases, through a combination of basic and translational research programs. This means you can contribute to scientific advances that have a direct impact on people afflicted with these diseases, including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies, and asthma. BRI research leadership has identified Bioinformatics as a key enabling technology, so there is broad and strong support for the analysis, and visualization of research data.  
Requisition number
1740
Department
Bioinformatics Group
Location : City
Seattle
Employment Type
Regular Full-Time
Combatting Immune Disease Through Systems Analysis    Come join our team and help fight immune diseases   We need individuals to apply cutting edge big data approaches to study of the human immune system. We believe that understanding how the immune system is broken in diseases like cancer and autoimmunity will lead to better patient care. We are looking for highly motivated and creative individuals who enjoy working in a multidisciplinary team-oriented environment to use Systems Biology approaches to help discover new mechanisms, biomarkers, and therapies for immune diseases. Successful candidates will receive a unique system of co-mentoring. They will reside in the Center for Systems Immunology at BRI and receive primary mentorship and training there. They will also collaborate closely with and be co-mentored by world class investigators expert in varied immune diseases and disease models throughout the Institute and elsewhere.
Requisition number
1741
Department
Bioinformatics Group
Location : City
Seattle
Employment Type
Regular Full-Time
The Clinical Research Program (CRP) Specialist provides administrative support and independently coordinates projects within the CRP at Benaroya Research Institute. The CRP supports the implementation of clinical research studies at Virginia Mason Medical Center and the Benaroya Research Institute.
Requisition number
1742
Department
Clinical Research Center
Location : City
Seattle
Employment Type
Regular Full-Time